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. 2022 Apr 22;28:1610297. doi: 10.3389/pore.2022.1610297

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Copyright © 2022 Ladányi, Hegyi, Balatoni, Liszkay, Rohregger, Waldnig, Dudás and Ferrone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–C) Average HLA class I expression of melanoma cells (% of stained area) in pre-treatment (Pre) and post-treatment (Post) metastases from ipilimumab-treated patients, labeled by HLA class I subunit-specific mAbs HCA2 (A), HC10 (B) and NAMB-1 (C). (D,E) Decrease of mean expression (% of stained area) (D) and of staining intensity (E) in post-treatment metastases as compared to autologous pre-treatment metastases from ipilimumab-treated patients, stained by HLA class I subunit-specific mAbs.