Fig. 2. In vitro characterisation of DVP ADCs. (a) HIC trace of C-ADC, (b) HIC trace of NC-ADC, (c) SEC traces of trastuzumab, NC-ADC and C-ADC, (d) HER2 ELISA of trastuzumab, NC-ADC and C-ADC. Error bars represent the standard deviation of biological quadruplicates, (e) cell viability of C-ADC against HER2-positive (+ve) and HER2-negative (−ve) cell lines, and (f) cell viability of NC-ADC against the same cell lines. Viability data shows the mean of three independent replicates and error bars represent S.E.M.
