FIG. 3.

Effects of SMAP29 or tobramycin treatment on the morphology of P. aeruginosa PAO1 evaluated by scanning electron microcopy. PAO1 was treated with media alone, tobramycin (5 μg/ml), or SMAP29 (0.5 μg/ml). At 1 min, 2 h, and 16 h the bacteria were processed for scanning electron microscopy. Within one minute, treatment with SMAP29 resulted in blebbing or blistering of the outer cell wall. The effects of tobramycin were much slower in their onset.