TABLE 1.
Sequences of cathelicidin peptides tested against clinical isolates from CF patients
| Peptide | Species | Peptide sequencea |
|---|---|---|
| LL37 | Human | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES |
| CAP-18 | Rabbit | GLRKRLRKFRNKIKEKLKKIGQKIQGLLPKLAPRTDY |
| CAP-18-18 | Rabbit | KRLRKFRNKIKEKLKKIG |
| CAP18-22 | Rabbit | RKRLRKFRNKIKEKLKKIGQKI |
| mCRAMP | Mouse | GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ |
| rCRAMP | Rat | GLVRKGGEKFGEKLRKIGQKIKEFFQKLALEIEQ |
| SMAP29 | Sheep | RGLRRLGRKIAHGVKKYGPTVLRIIRIAG |
| OV-1 | Sheep | KNLRRIIRKIIHIIKKYG |
| OV-2 | Sheep | LRRIIRKIIHIIKK-NH2b |
| OV-3 | Sheep | IRRIIRKIIHIIKK-NH2b |
a
Underlined amino acids are charged residues.
b
NH2 indicates C-terminal amidation.