Figure S12. Catalytically inactive derivatives of ARO1 have domain-specific effects on growth of C. albicans in liquid culture.

Cultures were grown in SC medium overnight at 30°C, subcultured into SC medium and SC medium supplemented with 0.05 μg/ml DOX overnight. Cultures were normalized to an OD₆₀₀ of 1, then diluted at 1:1,000 into 96-well plates containing 80 μl of SC medium (left) or SC medium supplemented with 5 μg/ml DOX (right). Growth at 30°C was monitored by optical density at 15-min intervals for 24 h. Data are mean OD₆₀₀ ± SD for quadruplicate cultures in a representative experiment of three performed.