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. Author manuscript; available in PMC: 2022 May 6.
Published in final edited form as: J Phys Chem B. 2021 Oct 28;125(44):12115–12124. doi: 10.1021/acs.jpcb.1c06330

Figure 3:

Figure 3:

Original potential U(Q) shows two states (Left, Right) separated by a barrier, which decreases when a force is applied. The rate constant kLR depends exponentially on the height of the barrier (vertical dashed line), which is the difference in energy between Q and QL. For small forces, the positions of QL, QR, and Q do not move much, but it is evident here that this force shifts the position of the transition state. In addition to the barrier, the applied force also decreases the energy difference between the two states, ΔERL.