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. Author manuscript; available in PMC: 2022 May 6.
Published in final edited form as: J Phys Chem B. 2021 Oct 28;125(44):12115–12124. doi: 10.1021/acs.jpcb.1c06330

Figure 5:

Figure 5:

Schematic of GPR68 activation by flow. Structures shown are homology models derived from inactive (left) and active (right) μ–opiod GPCR structures (4DKL, and 5C1M, respectively).