Table 2.
Adjusted hazard ratios for other site-specific cancers associated with dairy intakea
| Types | Never/rarely intake | Monthly intake | Regular intake | P trend | FDR-corrected P trendb | HR (95% CI) per 50 g/day of usual dairy intake | |||
|---|---|---|---|---|---|---|---|---|---|
| No. of cases | HR (95% CI) | No. of cases | HR (95% CI) | No. of cases | HR (95% CI) | ||||
| Oral cavity | 573 | 1.00 (0.89–1.12) | 98 | 0.97 (0.80–1.18) | 156 | 0.98 (0.82–1.18) | 0.83 | 0.90 | 1.00 (0.83–1.20) |
| Oesophagus | 1953 | 1.00 (0.95–1.06) | 209 | 0.89 (0.78–1.02) | 306 | 1.07 (0.94–1.21) | 0.73 | 0.90 | 1.03 (0.92–1.15) |
| Stomach | 2495 | 1.00 (0.95–1.05) | 338 | 1.06 (0.95–1.17) | 744 | 1.08 (1.00–1.18) | 0.10 | 0.34 | 1.07 (0.99–1.16) |
| Colon-rectum | 2066 | 1.00 (0.94–1.06) | 385 | 1.10 (1.00–1.21) | 899 | 1.09 (1.01–1.18) | 0.06 | 0.26 | 1.08 (1.00–1.17) |
| Pancreas | 605 | 1.00 (0.89–1.12) | 74 | 0.96 (0.76–1.20) | 207 | 1.11 (0.95–1.31) | 0.33 | 0.70 | 1.09 (0.93–1.29) |
| Larynx | 142 | 1.00 (0.81–1.24) | 19 | 0.79 (0.05–1.23) | 48 | 1.08 (0.77–1.52) | 0.86 | 0.90 | 1.05 (0.74–1.47) |
| Lung | 4185 | 1.00 (0.96–1.04) | 667 | 1.02 (0.94–1.10) | 1430 | 1.03 (0.96–1.09) | 0.48 | 0.82 | 1.03 (0.96–1.09) |
| Kidney | 258 | 1.00 (0.85–1.18) | 45 | 1.01 (0.76–1.35) | 147 | 1.21 (0.99–1.48) | 0.15 | 0.43 | 1.18 (0.96–1.46) |
| Bladder | 368 | 1.00 (0.87–1.14) | 66 | 1.04 (0.82–1.32) | 134 | 0.84 (0.69–1.02) | 0.19 | 0.46 | 0.91 (0.75–1.11) |
| Leukaemia | 453 | 1.00 (0.88–1.13) | 76 | 1.12 (0.89–1.39) | 133 | 0.96 (0.79–1.18) | 0.90 | 0.90 | 0.92 (0.75–1.13) |
| Prostate | 278 | 1.00 (0.85–1.17) | 40 | 0.93 (0.69–1.27) | 107 | 0.95 (0.76–1.19) | 0.70 | 0.90 | 0.97 (0.77–1.22) |
| Cervix | 847 | 1.00 (0.91–1.09) | 155 | 0.97 (0.83–1.14) | 257 | 1.09 (0.93–1.26) | 0.44 | 0.82 | 1.07 (0.92–1.25) |
| Endometrium | 292 | 1.00 (0.85–1.17) | 53 | 1.07 (0.82–1.40) | 123 | 0.94 (0.76–1.16) | 0.72 | 0.90 | 1.00 (0.80–1.25) |
| Ovary | 324 | 1.00 (0.86–1.16) | 54 | 0.91 (0.70–1.19) | 129 | 0.98 (0.79–1.20) | 0.79 | 0.90 | 1.03 (0.83–1.29) |
CI confidence interval, FDR false discovery rate, HR hazard ratio
aCox regression analyses were performed among 510,146 participants with no prior self-reported history of cancer at baseline. Analyses were stratified by age-at-risk (continuous variable), sex (dichotomous variable) and individual regions (ten regions) and were adjusted for education (four categories), income (four categories), smoking (four categories), alcohol consumption (four categories), total physical activity (continuous variable), family history of cancer (dichotomous variable), fresh fruit consumption (five categories), soy consumption (three categories) and body mass index (continuous variable)
bSignificance was assessed at a 5% FDR