Table 3.
Effect of seasonal malaria chemoprevention on incidence of uncomplicated and severe malaria cases
| Period | Mean incidence rates (100 persons-months) | Comparison | Intervention | IRRa ratios (%) (95% CI) | p | |
|---|---|---|---|---|---|---|
| Comparison districts (n = 11) | Intervention districts (n = 8) | IRR (95% CI) | IRR (95% CI) | |||
| Uncomplicated malaria | ||||||
| Before | 12.7 | 15.0 | 1 | 1 | 1 | |
| After | 13.2 | 10.7 | 1.05 (0.92–1.20) | 0.72 (0.63–0.82) | 69 (55–86) | 0.001 |
| Severe malaria | ||||||
| Before | 7.0 | 8.9 | 1 | 1 | 1 | |
| After | 7.5 | 7.0 | 1.08 (0.93–1.27) | 0.79 (0.68–0.91) | 73 (55–95) | 0.018 |
IRR incidence rate ratio obtained from a mixed-effects negative binomial regression model with random intercept for health districts and robust standard error
aRatio of IRR intervention vs. IRR comparison