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. 2022 May 6;22:504. doi: 10.1186/s12885-022-09561-w

Fig. 1.

Fig. 1

Overview of the model. On the left, the decision tree is visualized in which the margin status after navigated and standard surgery is incorporated. On the right, the Markov model is shown which is used to model the costs and effects after having a negative or positive surgical margin. It also shows the tunnel states used to incorporate time effects on the transition from progression to death due to progression