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. 2022 May 6;22:504. doi: 10.1186/s12885-022-09561-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visithttp://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — A and C show Cost-effectiveness planes for LARC (A) and LRRC (C) showing the incremental Quality Adjusted Life Years (QALYs) per incremental costs for navigated surgery versus standard surgery. The scatterplots show the mean differences in costs and outcomes from the data using 2000 bootstrap replicates. In both indications, most of the observations are in the North-East quadrant which indicates improved outcomes at higher costs. B and D show Cost-Effectiveness Acceptability Curves for LARC (B) and LRRC (D) presenting the probability of the cost-effectiveness of navigated surgery and standard surgery for a range of willingness to pay thresholds