TABLE 6.
MICs of comparator quinolones for the parent strain and transformants that were constructed with either GyrA or ParC double-mutation DNA
| Strain | MIC (μg/ml) of:
|
|||
|---|---|---|---|---|
| BMS- 284756 | Ciprofloxacin | Levofloxacin | Moxifloxacin | |
| R6 parent | 0.015 | 0.5 | 1 | 0.125 |
| Double GyrA transformant | 0.5 | 4 | 8 | 2 |
| Double ParC transformant | 1 | 16 | 16 | 4 |