Table 1.
Clinical characteristics
All patients(n = 894) | |
---|---|
Sex, n (%) | |
Male | 546 (61.1) |
Female | 348 (38.9) |
Age, mean (SD) | 54.93 (12.62) |
Disease, n (%) | |
Leukemia | 420 (47.0) |
Lymphoma | 166 (18.6) |
MDS/MPN | 199 (22.3) |
Multiple myeloma | 93 (10.4) |
Nonmalignant | 16 (1.8) |
Intensity, n (%) | |
Ablative | 589 (65.9) |
Reduced intensity | 191 (21.4) |
Nonablative | 114 (12.8) |
Total body irradiation, n (%) | 273 (30.5) |
Donor match, n (%) | |
Related haploidentical | 44 (4.9) |
Related identical | 288 (32.2) |
Related nonidentical | 4 (0.4) |
Unrelated identical | 447 (50.0) |
Unrelated nonidentical | 111 (12.4) |
Grafts, n (%) | |
BM | 86 (9.6) |
PBSCs, | 361 (40.4) |
PBSCs, CD34+ | 447 (49.9) |
GVHD (first 100 d), n (%) | 346 (39.8) |
Grade 0-1 | 628 (70.2) |
Grade 2-4 | 266 (29.8) |
Lower gut GVHD | 84 (9.4) |
Grade 0-1 | 855 (95.6) |
Grade 2-4 | 39 (4.4) |
MDS, myelodysplastic syndrome; MPN, myeloproliferative neoplasm; SD, standard deviation.