Anti-cancer activity of the isolated compounds.
| Compounds | HL-60 (μM) | Jurkat (μM) | K562 (μM) | HepG2 (μM) | MCF-7 (μM) | SGC-7901 (μM) | MDCK (μg mL−1) | YAC-1 (μg mL−1) | SMMC-7721 (μg mL−1) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | >40 | >40 | >40 | 9.95 | >40 | 39.5 | 287.38 | 5.38 | 2.84 |
| 4 | 20.58 | 16.96 | 17.65 | 8.17 | >40 | 9.92 | —a | —a | —a |
| 5 | 18.28 | 13.46 | 15.25 | 7.14 | >40 | 7.32 | —a | —a | —a |
| 7 | 3.11 | 4.32 | 5.25 | 1.14 | 1.51 | 1.72 | 5.12 | —a | —a |
| 8 | 3.50 | 3.95 | 4.35 | 1.13 | 1.23 | 1.85 | —a | —a | —a |
| 9 | 2.45 | 2.84 | 2.76 | 0.16 | 0.56 | 0.44 | 51.16 | 24.23 | —a |
| 10 | 2.92 | 4.21 | 3.14 | 1.13 | 0.89 | 0.34 | 22.57 | 12.83 | 16.17 |
| 11 | 2.41 | 4.54 | 3.24 | 1.16 | 1.02 | 0.59 | —a | —a | —a |
| 10-Hydroxycamptothecin | 0.04 | 0.03 | 1.60 | 11.90 | 16.81 | 19.80 | —a | —a | —a |
| Cisplatin | 1.92 | 3.66 | 17.63 | 4.58 | 57.25 | 5.79 | —a | —a | —a |
a
Not determined.