Synthesis of 9-monoalkylfluorene derivatives^a.

Entry	Alcohol	Product	Isolated yield (%)
1			98
2			99
3			96
4			99
5b			95
6			99
7			99
8			99
9			99
10			99
11b,c			99
12b,c			99
13b,d			97
14b,c			99
15b,c			99
16b,d			99
17b,e,f			89
18b,e,f			90
19g			99
20b,e,f			85
21c			99
22b,e,f			81

^aReaction conditions: fluorene (0.5 mmol), alcohols (1.5 mmol), t-BuOK (0.25 mmol), toluene (4 mL), in N₂.

^b24 h.

^c t-BuOK (0.375 mmol).

^d t-BuOK (0.50 mmol).

^e t-BuOK (0.75 mmol).

^f140 °C.

^g2-Bromo-9-fluorene was used.