TABLE 1.
REGARDS participant data
| Controls (N = 641) | ICI (N = 641) | Acute decliners (N = 537) | Progressive decliners (N = 104) | |
|---|---|---|---|---|
| Age (years) | 74.94 (8.62) | 74.96 (8.72) | 74.40 (5.23) | 77.87 (8.10)* , a |
| Sex (F:M) | 347:294 | 347:294 | 277:260 | 70:34* , a |
| Region (NB:BELT:BUCKLE) | 258:243:140 | 258:243:140 | 219:201:117 | 39:42:23 |
| Education (< HS:HS:SC:CG+) | 75:191:171:204 | 75:191:171:204 | 60:167:141:169 | 15:24:30:35 |
| Race (B:W) | 244:397 | 244:397 | 209:328 | 35:69 |
| Time to conversion or censoring (days) | 1081.32 (451.35) | 1000.69 (468.36)* | 1022.93 (481.60)* | 885.88 (374.35)* , a |
| Number of SIS assessments | 8.85 (2.03) | 8.81 (2.04) | 8.73 (2.11) | 9.19 (1.59) a |
| Minimum SIS score | 5.17 (0.38) | 3.27 (1.12)* | 3.54 (0.90)* | 1.86 (1.07)* , a |
| Framingham stroke risk score | 10.94 (9.61) | 11.66 (9.59) | 11.31 (9.67) | 13.48 (9.02)* |
Abbreviations: B, Black; CG+, college graduate or above; F, female; ICI, incident cognitive impairment; M, male; NB, nonbelt; HS, high school; REGARDS, Reasons for Geographic and Racial Differences in Stroke Study; SC, some college; SIS, Six‐Item Screener;nW, White.
Notes: Metric variables are shown as mean (standard deviation) and compared to t‐test. Categorical variables were compared using χ2.
*
P < .05 compared to controls with t‐test or χ2;
a
P < .05 compared to acute decliners. For Framingham stroke risk, controls, ICI, acute, progressive groups have n = 574, 552, 463, and 89, respectively.