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. 2022 Apr 22;14:872867. doi: 10.3389/fnagi.2022.872867

TABLE 1.

Demographic and clinical characteristics.

Controls n = 66 Relatives n = 103 PwP n = 163 Statistic
Mean age in years (SD) 41.16 (12.69) 45.93c (14.24) 40.18c (12.65) F(2,329) = 6.26, p = 0.002
Female sex 35 (53.0%) 65c (63.1%) 68c (41.7%) χ2(2,332) = 11.75, p = 0.003
Racial/ethnic minority identity 6a (9.1%) 13c (12.6%) 52ac (31.9%) χ2(2,332) = 21.36, p < 0.001
Parent education 5.77 (1.18) 5.56 (1.22) 5.39 (1.28) H(2) = 4.44, p = 0.108
Participant education (years) 16.08ab (2.27) 15.10bc (2.30) 13.96ac (2.02) F(2,329) = 24.62, p < 0.001
BMI (kg/m2) 26.15a (5.18) 28.39c (5.93) 31.25ac (7.40) F(2,328) = 15.60, p < 0.001
BPRS total 27.03ab (3.51) 32.41bc (6.84) 44.87ac (12.45) F(2,329) = 100.44, p < 0.001
SPQ total 7.85ab (7.51) 14.96bc (13.09) 31.14ac (16.33) F(2,327) = 81.12, p < 0.001
PID-5 negative affect 0.89a (0.32) 0.98c (0.37) 1.31ac (0.42) F(2,320) = 35.82, p < 0.001
WAIS IQ 109.09ab (12.28) 101.88bc (11.35) 97.40ac (12.15) F(2,328) = 22.81, p < 0.001

Groups that share a superscript reflect a significant (p < 0.05) pairwise comparison; Participant racial/ethnic identities were as follows, in order of group (controls/relatives/PwP): 90.9/87.4/68.1% White, 4.5/6.8/20.9% Black, 1.5/2.9/3.7% Latino/a, 1.5/1.0/3.1% Asian/Asian American, 0/0/0.6% Native American, 1.5/1.9/3.7% Other; Number of participants who were missing data: nine on parent education, two on SPQ and one on WAIS IQ; Parent education = highest of either parent’s level of education achieved, coded on an ordinal scale: 1 = 7th grade or less, 2 = 7th–9th grade, 3 = 10th–12th grade, 4 = high school graduate/GED, 5 = partial college/vocational/technical/RN, 6 = 4 year college/university graduate, 7 = graduate degree; BMI = body mass index calculated as [weight/(height * height)] and then multiplied by 703 to convert to metric units; BPRS = Brief Psychiatric Rating Scale (minimum score = 24); SPQ = Schizotypal Personality Questionnaire; PID-5 = Personality Inventory for DSM-5; WAIS IQ = estimated from Wechsler Adult Intelligence Scale.