Figure 1.

Random forest (RF) variable importance plot in treatment-naïve, newly diagnosed pediatric IBD patients and controls. Mean decrease accuracy is the measure of the performance of the model without each amino acid. A higher value indicates the importance of that amino acid in predicting group (IBD vs controls). The amino acids in dark blue indicate higher median concentrations in IBD. The amino acid in gray did not significantly differ (P ≥ .05) between groups based on a Mann-Whitney U test.