Table 3. The top three most similar pairs of cancer networks based on the H_JS distance of the three-node subgraphs and four-node subgraphs normalized frequency distributions.

Network A	Network B	HJS distance	Absolute value of the difference of the subgraph normalized frequency distributions
3-node subgraph ID			(ID 6, ID 12, ID 36, ID 38)
Acute myeloid leukaemia (AML)	Pancreatic cancer	0.0214	(0.013, 0.007, 0.021, 0.002)
Chronic myeloid leukaemia (CML)	Gastric cancer	0.0309	(0.038, 0.020, 0.018, null)
Gastric cancer	Small cell lung cancer	0.0339	(0.024, 0.042, null, 0.018)
4-node subgraph ID			(ID 14, ID 28, ID 74, ID 76, ID 78, ID 280, ID 328, ID 392, ID 2184)
Gastric cancer	Hepatocellular carcinoma	0.0998	(0.001, 0.027, 0.063, 0.011, null, 0.001, 0.045, 0.046, 0.006)
Chronic myeloid leukaemia (CML)	Melanoma	0.138	(0.009, 0.049, 0.114, 0.017, null, 0.028, 0.016, 0.016, null)
Hepatocellular carcinoma	Small cell lung cancer	0.138	(0.115, 0.006, 0.025, 0.015, null, 0.004, 0.004, 0.065, 0.002)