Table 1.
Item | Recommendation | Evidence Level | Recommendation Grade |
---|---|---|---|
1. Preadmission information, education, and counseling | Patients should receive detailed preoperative counseling. | Moderate | Strong |
2. Preadmission optimization | For daily smokers, 1 mo of abstinence before surgery is beneficial. For patients who are obese, weight reduction to achieve a BMI ≤30 kg/m2 before surgery is beneficial. For alcohol abusers, 1 mo of abstinence before surgery is beneficial. For appropriate groups, referral should be made to resources for these behavior changes. | Moderate (smoking) High (obesity) Low (alcohol) | Strong Strong Strong |
3. Perforator flap planning | If preoperative perforator mapping is required, CTA is recommended. | Moderate | Strong |
4. Perioperative fasting | Preoperative fasting should be minimized and patients should be allowed to drink clear fluids up to 2 hr before surgery. | Moderate | Strong |
5. Preoperative carbohydrate loading | Preoperative maltodextrin-based drinks should be given to patients 2 hr before surgery. | Low | Strong |
6. Venous thromboembolism prophylaxis | Patients should be assessed for venous thromboembolism risk, Unless contraindicated, and balanced by the risk of bleeding, patients at a higher risk should receive low-molecular-weight heparin or unfractionated heparin until ambulatory or discharged. Mechanical methods should be added. | Moderate | Strong |
7. Antimicrobial prophylaxis | Chlorhexidine skin preparation should be performed and intravenous antibiotics covering common skin organisms should be given within 1 hr of incision. | Moderate | Strong |
8. Postoperative nausea and vomiting prophylaxis | Women should receive preoperative and intraoperative medications to mitigate postoperative nausea and vomiting. | Moderate | Strong |
9. Preoperative and intraoperative analgesia | Women should receive multimodal analgesia to mitigate pain. | Moderate | Strong |
10. Standard anesthetic protocol | General anesthesia with TIVA is recommended. | Moderate | Strong |
11. Preventing intraoperative hypothermia | Preoperative and intraoperative measures, such as forced air, to prevent hypothermia should be instituted. Temperature monitoring is required to ensure the patient’s body temperature is maintained above 36°C. | Moderate | Strong |
12. Perioperative intravenous fluid management | Overresuscitation or underresuscitation of fluids should be avoided and water and electrolyte balance should be maintained. Goal-directed therapy is a useful method of achieving these goals. Balanced crystalloid solutions, rather than saline, is recommended. Vasopressors are recommended to support fluid management and do not negatively affect free flaps. | Moderate | Strong |
13. Postoperative analgesia | Multimodal postoperative pain management regimens are opioid-sparing and should be used. | High | Strong |
14. Early feeding | Patients should be encouraged to take fluids and food orally as soon as possible, preferably within 24 hr after surgery. | Moderate | Strong |
15. Postoperative flap monitoring | Flap monitoring within the first 72 hr should occur frequently. Clinical evaluation is sufficient for monitoring, with implantable Doppler devices recommended in cases of buried flaps. | Moderate | Strong |
16. Postoperative wound management | For incisional closure, conventional sutures are recommended. Complex wounds following skin necrosis are treatable with debridement and negative-pressure wound therapy. | High (sutures) Moderate (NPWT) | Strong |
17. Early mobilization | Patients should be mobilized within the first 24 hr after surgery. | Moderate | Strong |
18. Postdischarge home support and physiotherapy | Early physiotherapy, supervised exercise programs, and other supportive care initiatives should be instituted after discharge. | Moderate | Strong |
BMI, body mass index; CTA, computed tomographic angiography; TIVA, total intravenous anesthesia; NPWT, negative-pressure wound therapy.