Table 1.

Results of consecutive pharmacogenetic DPYD evaluations in patients with 12 GI cancer.

Patient number	Primary tumor	Type of tissue specimen (biopsy or surgical material)	DPYD tissue result	DPYD blood result	MSI status (MSS vs MSIH)
1	Colon	Surgical material	omo wt	omo wt	MSS
2	Colon	Surgical material	G2194A hetero g/a (c.2194 G>A; V7321I)	G2194A hetero g/a (c.2194 G>A; V7321I)	MSS
3	Colon	Biopsy	omo wt	omo wt	MSS
4	Colon	Surgical material	omo wt	omo wt	MSS
5	EGJ	Biopsy	omo wt	omo wt	MSS
6	Colon	Surgical material	G2194A hetero g/a (c.2194 G>A; V7321I)	G2194A hetero g/a (c.2194 G>A; V7321I)	MSS
7	Colon	Surgical material	G2194A hetero g/a (c.2194 G>A; V7321I)	G2194A hetero g/a (c.2194 G>A; V7321I)	MSS
8	Colon	Surgical material	G2194A hetero g/a (c.2194 G>A; V7321I)	G2194A hetero g/a (c.2194 G>A; V7321I)	MSS
9	Pancreas	Biopsy	omo wt	omo wt	MSS
10	Colon	Biopsy	omo wt	omo wt	MSS
11	Colon	Surgical material	omo wt	omo wt	MSS
12	EGJ	Biopsy	G2194A hetero g/a (c.2194 G>A; V7321I)	G2194A hetero g/a (c.2194 G>A; V7321I)	MSS

Abbreviations: M, male; F, female; EGJ, esophagogastric junction; GI, gastrointestinal; wt, wild type; hetero, heterozygote; MSS, microsatellite stable; 
MSI-H, high microsatellite instability.