Table 3.

Cox Proportional‐Hazard Regression Analysis of MACEs

Variable	Multivariable analysis 1			Multivariable analysis 2			Multivariable analysis 3
	HR	95% CI	P value	HR	95% CI	P value	HR	95% CI	P value
CSF at hyperemia, mL/min per g	0.64	0.47–0.88	0.005			Not selected			Not selected
Corrected g‐CFR			Not selected	0.62	0.47–0.82	0.001			Not selected
Concordantly impaired h‐CSF and g‐CFR			Not selected			Not selected	2.80	1.68–4.65	<0.001

Adjusted for age, Killip class 3 or 4, log (NT‐proBNP [N‐terminal pro‐B‐type natriuretic peptide]), left ventricular mass index, and late gadolinium enhancement. CSF indicates coronary sinus flow; g‐CFR, global coronary flow reserve; h‐CSF, hyperemic CSF; HR, hazard ratio; and MACE, major adverse cardiac event.