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. 2022 Feb 28;11(5):e022770. doi: 10.1161/JAHA.121.022770

Table 1.

Baseline Characteristics, Coronary Anatomy, and Procedural Details of Patients With Multivessel Coronary Artery Disease Undergoing Nonemergent Angiography

Variable Hospital PCI/CABG ratio

Low (0.70–0.85)

n=17 487

Medium (1.01–1.17) n=15 275

n=15 275

High (1.18–1.29)

n=11 526

P value
Age, y, mean±SD 67.2±10.6 66.8±11.0 66.9±11.3 <0.01
Male sex, n (%) 13 331 (76.2%) 11 588 (75.9%) 8801 (76.4%) 0.60
Income quintile, n (%) <0.01
1, lowest 3458 (19.8%) 3045 (19.9%) 2702 (23.4%)
2 3517 (20.1%) 3150 (20.6%) 2643 (22.9%)
3 3584 (20.5%) 3088 (20.2%) 2597 (22.5%)
4 3609 (20.6%) 3117 (20.4%) 1692 (14.7%)
5, highest 3283 (18.8%) 2852 (18.7%) 1858 (16.1%)
Missing 36 (0.2%) 23 (0.2%) 34 (0.3%)
Rural, n (%) 3351 (19.2%) 2592 (17.0%) 316 (2.7%) <0.01
Charlson index, mean±SD 2.0±1.9 1.9±1.7 2.0±1.7 0.01
Hypertension, n (%) 12 375 (70.8%) 10 623 (69.5%) 8422 (73.1%) <0.01
Diabetes, n (%) 5986 (34.2%) 5469 (35.8%) 4508 (39.1%) <0.01
Smoking status, n (%)
Current 3528 (20.2%) 3675 (24.1%) 1733 (15.0%) <0.01
Former 6408 (36.6%) 3723 (24.4%) 2953 (25.6%)
Never 6399 (36.6%) 7150 (46.8%) 6210 (53.9%)
Canadian Cardiovascular Society class, n (%)* <0.01
0 1307 (7.5%) 1823 (11.9%) 1389 (12.1%)
1 1165 (6.7%) 1199 (7.8%) 1280 (11.1%)
2 2857 (16.3%) 2863 (18.7%) 2835 (24.6%)
3 2093 (12.0%) 2033 (13.3%) 1389 (12.1%)
4 473 (2.7%) 554 (3.6%) 312 (2.7%)
ACS low risk 3051 (17.4%) 2224 (14.6%) 737 (6.4%)
ACS intermediate risk 4676 (26.7%) 2916 (19.1%) 2865 (24.9%)
ACS high risk 1528 (8.7%) 1599 (10.5%) 690 (6.0%)
Unknown 337 (1.9%) 64 (0.4%) 29 (0.3%)
Congestive heart failure, n (%) 1224 (7.0%) 1141 (7.5%) 770 (6.7%) 0.04
Previous myocardial infarction, n (%) 4126 (23.6%) 2800 (18.3%) 2513 (21.8%) <0.01
Peripheral vascular disease, n (%) 1287 (7.4%) 1103 (7.2%) 695 (6.0%) <0.01
Cerebrovascular disease, n (%) 1376 (7.9%) 982 (6.4%) 743 (6.4%) <0.01
Chronic obstructive pulmonary disease, n (%) 1181 (6.8%) 1060 (6.9%) 462 (4.0%) <0.01
Creatinine, mean±SD 97.4±74.6 100.1±95.9 103.3±94.1 <0.01
Dialysis, n (%) 287 (1.6%) 242 (1.6%) 296 (2.6%) <0.01
Estimated glomerular filtration rate, n (%) <0.01
<30 526 (3.0%) 507 (3.3%) 482 (4.2%)
30–59 2981 (17.0%) 2294 (15.0%) 1846 (16.0%)
60–89 7861 (45.0%) 6206 (40.6%) 5137 (44.6%)
≥90 5220 (29.9%) 4433 (29.0%) 3596 (31.2%)
Missing 899 (5.1%) 1835 (12.0%) 465 (4.0%)
Left main disease, n (%) 4075 (23.3%) 3295 (21.6%) 2023 (17.6%) <0.001
3‐VD with proximal LAD, n (%) 3036 (17.4%) 2168 (14.2%) 2147 (18.6%) <0.01
3‐VD without proximal LAD, n (%) 3440 (19.7%) 3439 (22.5%) 2418 (21.0%) <0.01
2‐VD with LAD, n (%) 6936 (39.7%) 6373 (41.7%) 4938 (42.8%) <0.01
PCI, n (%) 6774 (38.7%) 8055 (52.7%) 6989 (60.6%) <0.01
Physician performing index angiogram, n (%) <0.01
Diagnostic cardiologist 2430 (13.9%) 2558 (16.7%) 3338 (29.0%)
Interventional cardiologist 15 057 (86.1%) 12 717 (83.3%) 8188 (71.0%)
Hospital type, n (%) <0.01
Community 8969 (51.3%) 8010 (52.4%) 5169 (44.8%)
Teaching 8518 (48.7%) 7265 (47.6%) 6357 (55.2%)
Hospital capability, n (%) <0.01
Angiography only 0 (0.0%) 0 (0.0%) 1647 (14.3%)
Angiography and PCI only 2620 (15.0%) 4677 (30.6%) 3522 (30.6%)
Angiography, PCI and CABG 14 867 (85.0%) 10 598 (69.4%) 6357 (55.2%)
Primary reason for referral, n (%) <0.01
E: elective, stable coronary Disease 4180 (23.9%) 4103 (26.9%) 4855 (42.1%)
N: non–ST‐segment–elevation myocardial infarction 6998 (40.0%) 5633 (36.9%) 3274 (28.4%)
R: rule out coronary artery disease 2091 (12.0%) 2241 (14.7%) 1152 (10.0%)
U: unstable angina 3362 (19.2%) 2517 (16.5%) 1907 (16.5%)
O: other 856 (4.9%) 781 (5.1%) 338 (2.9%)

ACS indicates acute coronary syndrome; CABG, coronary artery bypass grafting; LAD, left anterior descending; PCI, percutaneous coronary intervention; and VD, vessel disease.