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. 2022 Feb 16;11(5):e022768. doi: 10.1161/JAHA.121.022768

Table 2.

Risk of Parkinson Disease and Secondary Parkinsonism in Patients With MI and Members of the General Population Comparison Cohort

Disease Comparison cohort Patients with MI
Events/No. at risk Cumulative incidence,% (95% CI) Events/No. at risk Cumulative incidence,% (95% CI) Hazard ratio controlled for matching factors (95% CI)* Adjusted hazard ratio (95% CI)
Parkinson disease 4352/630 166 1.25 (1.20–1.29) 668/131 396 0.86 (0.79–0.94) 0.82 (0.75–0.89) 0.80 (0.73–0.87)
Secondary parkinsonism 474/630 166 0.14 (0.12–0.16) 71/131 396 0.09 (0.07–0.12) 0.77 (0.59–1.00) 0.72 (0.54–0.94)

MI indicates myocardial infarction.

*

Age, sex, and calendar year.

Controlled for matching factors by study design and adjusted for heart failure, stable angina pectoris, atrial fibrillation/atrial flutter, valvular heart disease, hypercholesterolemia, hypertension, stroke, intermittent claudication, obesity, diabetes, chronic pulmonary disease, alcoholism‐related disease, head trauma, osteoarthritis, anemia, chronic kidney disease, depression, a modified Charlson Comorbidity Index score, antipsychotics, calcium channel blockers, income, and employment.