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. 2019 Nov 11;9(63):36690–36698. doi: 10.1039/c9ra07002h

Antiproliferation of 5-acetamido-1-(methoxybenzyl) isatin on tumor cell lines in vitro.

Cell line IC50 (μM)
CPT 5-Acetamido-1-(methoxybenzyl) isatin
Human leukemia (K562) 0.08 ± 0.004 0.29 ± 0.003
Human prostate cancer (PC-3) 1.49 ± 0.08 0.38 ± 0.06
Liver cancer (HepG2) 0.07 ± 0.02 0.42 ± 0.08
Human breast cancer (MCF-7) 0.37 ± 0.05 3.37 ± 0.86
Non-small cell lung cancer (H460) 0.04 ± 0.002 28.40 ± 14.40
Human colon cancer (HT-29) 0.04 ± 0.02 34.37 ± 6.30