Antiproliferation of 5-acetamido-1-(methoxybenzyl) isatin on tumor cell lines in vitro.
| Cell line | IC50 (μM) | |
|---|---|---|
| CPT | 5-Acetamido-1-(methoxybenzyl) isatin | |
| Human leukemia (K562) | 0.08 ± 0.004 | 0.29 ± 0.003 |
| Human prostate cancer (PC-3) | 1.49 ± 0.08 | 0.38 ± 0.06 |
| Liver cancer (HepG2) | 0.07 ± 0.02 | 0.42 ± 0.08 |
| Human breast cancer (MCF-7) | 0.37 ± 0.05 | 3.37 ± 0.86 |
| Non-small cell lung cancer (H460) | 0.04 ± 0.002 | 28.40 ± 14.40 |
| Human colon cancer (HT-29) | 0.04 ± 0.02 | 34.37 ± 6.30 |