Table 1.
Disease severity | Recommended drugs |
---|---|
Not requiring hospitalization |
Bamlanivimab plus etesevimab or Casirivimab plus imdevimab or Sotrovimab Do not use dexamethasone or other corticosteroids |
Discharged from hospital in stable conditions and not requiring supplemental oxygen | Do not use dexamethasone, remdesivir, or baricitinib |
Discharged from hospital and requiring supplemental oxygen | Insufficient evidence to recommend or not continuing the in-hospital therapy with remdesivir, dexamethasone, and/or baricitinib |
Discharged from hospital and increasing need for supplemental oxygen | Dexamethasone for the duration of supplemental oxygen |
Hospitalized and not requiring supplemental oxygen |
Insufficient evidence to recommend or not remdesivir Do not use dexamethasone or other corticosteroids |
Hospitalized and requiring supplemental oxygen | Remdsivir or Dexamethasone Or Dexamethasone + remdsivir |
Hospitalized and requiring supplemental oxygen through a high-flow device or non-invasive ventilation | Dexamethasone or Dexamethasone + remdsivir |
Hospitalized and requiring mechanical ventilation or extracorporeal membrane oxygenation |
Dexamethasone Dexamethasone + tocilizumab (or sarilumab, if tocilizumab unavailable) for patients who are within 24 h of admission to intensive care unit |