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The circled numbers refer to the following enzymes: ⅰ, SAH hydrolase; ⅱ, cystathionine‐β‐synthase; ⅲ, cystathionine‐γ‐ lyase; ⅳ, betaine‐homocysteine methlytransferase; ⅴ, methionine synthase; ⅵ, methionine adenosyltransferase; ⅶ, methyltransferases; ⅷ adenosine deaminase; ⅸ, phosphorylase; ⅹ, xanthine oxidase. SAH indicates S‐adenosyl‐L‐homocysteine; and SAM indicates S‐adenosyl‐methionine.
