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. 2021 Dec 22;11(1):e023371. doi: 10.1161/JAHA.121.023371

Figure 1. Testosterone and 17‐β estradiol levels in male patients with inflammatory diseases, during active disease (PRE) and after therapeutic interventions resulting in a C‐reactive protein decrease >75% (POST) when compared with the baseline.

Figure 1

A, Total testosterone; 2‐tailed Wilcoxon matched‐pairs test, ***P<0.001. Values below the horizontal dotted line indicate a female range (upper limit of reference values in premenopausal women, ie, 1.1 ng/mL). B, Free testosterone; 2‐tailed Wilcoxon matched‐pairs test, ***P<0.001. C, Bioavailable testosterone; 2‐tailed Wilcoxon matched‐pairs test, ***P<0.001. D, 17‐β estradiol; 2‐tailed Wilcoxon matched‐pairs test, **P<0.01. Values above the horizontal dotted line indicate a female range (lower limit of reference values in premenopausal women, ie, 100 pg/mL). Patients, n=22. Bioav indicates bioavailable; Estradiol, 17‐β estradiol; and T, testosterone.