Table 1.
Patient Characteristics According to Admission NT‐proBNP
|
Demographics, n or median (Q1 − Q3) |
Normal NT‐proBNP (n=3331) |
Elevated NT‐proBNP (n=1344) |
P value |
|---|---|---|---|
| Male | 1828 (54.9) | 735 (54.7) | 0.931 |
| Age, y | 63.0 (52.0–75.0) | 72.0 (61.0–83.0) | <0.001 |
| BMI, kg/m2 | 30.4 (25.9–35.7) | 27.6 (23.7–32.9) | <0.001 |
| CKD | 293 (8.8) | 463 (34.5) | <0.001 |
| Diabetes | 1224 (36.7) | 651 (48.4) | <0.001 |
| Heart failure | 301 (9.0) | 545 (40.6) | <0.001 |
| Hypertension | 2011 (60.4) | 1087 (80.9) | <0.001 |
| CABG/PCI/MI | 289 (8.7) | 103 (7.7) | 0.053 |
| Presenting labs | |||
| NT‐proBNP, pg/mL | 139 (50–366) | 4130 (2124–12 029) | <0.001 |
| Creatinine, mg/dL | 0.99 (0.76–1.30) | 1.60 (1.08–2.87) | <0.001 |
| Troponin, ng/L | 10.0 (0.0–30.0) | 50.0 (20.0–110.0) | <0.001 |
| CRP, mg/L | 70.0 (20.9–130.0) | 79.5 (22.3–159.0) | 0.011 |
| Ferritin, ng/mL | 567 (259–881) | 649 (307–1366) | <0.001 |
| d‐Dimer, ng/mL | 800 (400–1560) | 1428 (600–3094) | <0.001 |
| Procalcitonin, ng/mL | 0.14 (0.07–0.32) | 0.38 (0.14–1.50) | <0.001 |
| Vitals on admission | |||
| Heart rate, bpm | 93 (80–106) | 90 (76–105) | <0.001 |
| Systolic blood pressure, mm Hg | 132 (117–147) | 129 (111–148) | 0.003 |
| Diastolic blood pressure, mm Hg | 76 (67–85) | 72 (62–84) | <0.001 |
| Respiratory rate | 20 (18–24) | 20 (18–25) | 0.014 |
| SpO2% | 95 (92–97) | 95 (91–98) | 0.143 |
| Required supplemental oxygen | 916/2545 (36.0) | 562/1128 (49.8) | <0.001 |
BMI indicates body mass index; CABG, coronary artery bypass graft; CKD, chronic kidney disease; CRP, C‐reactive protein; MI, myocardial infarction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; PCI, percutaneous coronary intervention; and SpO2%, oxygen saturation.