Table 6.
Effects of Magnesium Oxide and Magnesium Sulfate (Versus Magnesium Citrate) on Blood Pressure
|
Magnesium oxide (n=46) |
Magnesium sulfate (n=46) |
Magnesium citrate (n=46) |
|
|---|---|---|---|
| Systolic blood pressure | |||
| 2‐wk | |||
| Mean, mm Hg | 127±15 | 130±15 | 131±14 |
| Difference vs magnesium citrate | 1 (−2 to 3) | 1 (−1 to 4) | … |
| 12‐wk | |||
| Mean, mm Hg | 125±14 | 129±13 | 132±15 |
| Difference vs magnesium citrate | −1 (−4 to 1) | −0 (−3 to 2) | … |
| 24‐wk | |||
| Mean, mm Hg | 127±15 | 131±16 | 133±16 |
| Difference vs magnesium citrate | −0 (−3 to 3) | 1 (−2 to 4) | … |
| Diastolic blood pressure | |||
| 2‐wk | |||
| Mean, mm Hg | 77±8 | 79±8 | 78±8 |
| Difference vs magnesium citrate | 0 (−1 to 2) | 0 (−1 to 2) | … |
| 12‐wk | |||
| Mean, mm Hg | 75±8 | 79±8 | 78±9 |
| Difference vs magnesium citrate | −1 (−2 to 1) | 0 (−1 to 2) | … |
| 24‐wk | |||
| Mean, mm Hg | 76±9 | 79±9 | 79±9 |
| Difference vs magnesium citrate | −0 (−2 to 1) | −1 (−2 to 1) | … |
| Mean arterial pressure | |||
| 2‐wk | |||
| Mean, mm Hg | 93±10 | 96±10 | 96±10 |
| Difference vs magnesium citrate | 1 (−1 to 3) | 1 (−1 to 2) | … |
| 12‐wk | |||
| Mean, mm Hg | 92±9 | 95±9 | 96±11 |
| Difference vs magnesium citrate | −0 (−2 to 1) | 0 (−2 to 2) | … |
| 24‐wk | |||
| Mean, mm Hg | 93±10 | 96±11 | 97±11 |
| Difference vs magnesium citrate | 0 (−1 to 2) | 0 (−2 to 2) | … |
| Pulse pressure | |||
| 2‐wk | |||
| Mean, mm Hg | 50±10 | 51±10 | 53±9 |
| Difference vs magnesium citrate | 1 (−2 to 3) | 1 (−1 to 3) | … |
| 12‐wk | |||
| Mean, mm Hg | 49±9 | 51±9 | 53±10 |
| Difference vs magnesium citrate | 1 (−3 to 2) | −1 (−3 to 2) | … |
| 24‐wk | |||
| Mean, mm Hg | 51±11 | 52±10 | 54±10 |
| Difference vs magnesium citrate | 0 (−2 to 2) | 1 (−1 to 3) | … |
| Heart rate | |||
| 2‐wk | |||
| Mean, bpm | 59±8 | 59±7 | 61±8 |
| Difference vs magnesium citrate | −1 (−3 to 1) | −0 (−2 to 1) | … |
| 12‐wk | |||
| Mean, bpm | 59±7 | 60±6 | 61±8 |
| Difference vs magnesium citrate | −1 (−3 to 0) | −0 (−2 to 1) | … |
| 24‐wk | |||
| Mean, bpm | 59±7 | 59±6 | 62±8 |
| Difference vs magnesium citrate | −3 (−5 to −1)* | −2 (−3 to −0) | … |
Values are mean±SD. Adjusted mean differences (90% CIs) were obtained from linear mixed‐effect models with age, sex, baseline value of the outcome of interest, time, intervention, and the interaction time×intervention as fixed effects.
*
P<0.01 (one‐sided P values).