Table 1.
Outcome |
No treatment (n=1069) |
Oral anticoagulants (n=283) |
Adjusted HR* |
Antiplatelet therapy (n=214) |
Adjusted HR † |
---|---|---|---|---|---|
Ischemic stroke | 0.61 (0.42–0.89) | 1.13 (0.81–1.56) | |||
No. of events | 52 | 10 | 15 | ||
Person‐y | 1068.81 | 327.18 | 271.16 | ||
Event rate (95% CI) | 48.69 (37.10–63.89) | 30.56 (16.45–56.81) | 55.32 (33.35–91.76) | ||
Thromboembolism | 0.60 (0.43–0.84) | 1.11 (0.84–1.48) | |||
No. of events | 68 | 12 | 18 | ||
Person‐y | 1065.08 | 325.29 | 263.12 | ||
Event rate (95% CI) | 63.84 (50.34–80.97) | 36.89 (20.95–64.96) | 68.41 (43.10–108.58) | ||
Intracerebral hemorrhage | 1.15 (0.66–2.02) | 1.81 (1.07–3.04) | |||
No. of events | 17 | 4 | 7 | ||
Person‐y | 1066.18 | 335.15 | 274.24 | ||
Event rate (95% CI) | 15.94 (9.91–25.65) | 11.94 (4.48–31.80) | 25.52 (12.17–53.54) | ||
Major bleeding event | 1.40 (0.99–1.98) | 1.10 (0.77–1.58) | |||
No. of events | 42 | 11 | 11 | ||
Person‐y | 1051.00 | 301.22 | 271.86 | ||
Event rate (95% CI) | 39.96 (29.53–54.07) | 33.50 (18.55–60.50) | 40.46 (22.41–73.06) | ||
All‐cause mortality | 0.85 (0.72–1.01) | 0.88 (0.75–1.03) | |||
No. of events | 235 | 48 | 45 | ||
Person‐y | 1087.31 | 336.22 | 278.89 | ||
Event rate (95% CI) | 216.13 (190.19–245.61) | 142.77 (107.59–189.45) | 161.35 (120.47–216.11) |
HR indicates hazard ratio.
Hazard ratio between oral anticoagulants and no treatment.
Hazard ratio between antiplatelet therapy and no treatment.