. 2021 Nov 15;10(23):e022303. doi: 10.1161/JAHA.121.022303

Table 2.

Summary Pooled OR (95% CI) Values for Main Outcomes

Variable	90‐d mRS score 0–2	Mortality	Recanalization	sICH	Any ICH
RCTs	1.08 (0.84–1.38), I²=0.0%, P=0.538	0.93 (0.66–1.31), I²=0.0%, P=0.690	0.77 (0.54–1.10), I²=0.0%, P=0.152	0.72 (0.43–1.22), I²=0.0%, P=0.222	0.68 (0.50–0.92), I²=23.3%, P=0.014
Observational studies	1.02 (0.86–1.21), I²=0.0%, P=0.854	1.03 (0.70–1.53), I²=57.5%, P=0.866	1.03 (0.79–1.35), I²=20.2%, P=0.837	0.66 (0.47–0.93), I²=0.0%, P=0.018	0.72 (0.57–0.90), I²=21.2%, P=0.004
Overall analysis	1.04 (0.90–1.19), I²=0.0%, P=0.615	1.03 (0.78–1.36), I²=45.8%, P=0.832	0.93 (0.76–1.14), I²=10.1%, P=0.486	0.68 (0.51–0.91), I²=0.0%, P=0.008	0.71 (0.60–0.84), I²=13.9%, P<0.001
East Asia	1.08 (0.91– 1.29), I²=0.0%, P=0.358	1.04 (0.83–1.30), I²=0.0%, P=0.762	1.01 (0.70–1.43), I²=40.4%, P=0.977	0.70 (0.51–0.95), I²=0.0%, P=0.024	0.69 (0.58–0.82), I²=0.0%, P<0.001
Western countries	0.96 (0.73–1.26), I²=6.0%, P=0.776	0.78 (0.35–1.73), I²=76.6%, P=0.534	0.88 (0.68–1.15), I²=0.0%, P=0.359	0.59 (0.29–1.21), I²=0.0%, P=0.148	0.80 (0.50–1.26), I²=33.0%, P=0.335
RCT+PSM	0.97 (0.84–1.13), I²=0.0%, P=0.723	1.07 (0.87–1.32), I²=0.0%, P=0.510	0.85 (0.66–1.09), I²=23.0%, P=0.201	0.66 (0.51–0.85), I²=0.0%, P=0.001	0.82 (0.68–0.98), I²=17.2%, P=0.030
RCT+observational studies with an NOS score >7	1.03 (0.89–1.20), I²=0.9%, P=0.665	1.04 (0.79–1.36), I²=42.6%, P=0.785	0.94 (0.73–1.20), I²=29.8%, P=0.611	0.68 (0.50–0.91), I²=0.0%, P=0.010	0.72 (0.62–0.85), I²=6.0%, P<0.001
Anterior circulation occlusion	1.01 (0.85–1.19), I²=0.0%, P=0.945	0.96 (0.67–1.37), I²=54.0%, P=0.810	1.00 (0.76–1.32), I²=24.8%, P=0.983	0.74 (0.52–1.07), I²=0.0%, P=0.110	0.68 (0.55–0.84), I²=20.0%, P<0.001

ICH indicates intracranial hemorrhage; mRS, modified Rankin Scale; NOS, Newcastle‐Ottawa Scale; OR, odds ratio; PSM, propensity score matching; RCT, randomized controlled trial; and sICH, symptomatic ICH.