Table 2.
Age‐ and Sex‐Specific HRs of CVD According to the Legislated Category of Health Intervention for Screened Participants
| Nonobese/overweight (reference) | Obese/overweight: lifestyle intervention | |||
|---|---|---|---|---|
| ISO | MSI | ISI | ||
| Waist <85 cm in men/<90 cm in women and BMI <25 kg/m2, regardless of risk factors |
Waist ≥85 cm in men/≥90 cm in women and 0 risk factor OR |
Waist ≥85 cm in men/≥90 cm in women and 1 risk factor OR |
Waist ≥85 cm in men/≥90 cm in women and ≥2 risk factors OR |
|
| waist <85 cm in men/<90 cm in women, BMI ≥25 kg/m2, and 0 risk factor | waist <85 cm in men/<90 cm in women, BMI ≥25 kg/m2, and 1 or 2 risk factors |
waist <85 cm in men/<90 cm in women, BMI ≥25 kg/m2, and ≥3 risk factors |
||
| Age, 40–64 y | ||||
| Men, n | 5443 | 588 | 1075 | 3389 |
| No. of patient‐y | 47 809 | 5003 | 8578 | 25 999 |
| No. of cases | 140 | 8 | 25 | 154 |
| Age‐ and area‐adjusted HR (95% CI) | 1.00 | 0.65 (0.32–1.33) | 0.97 (0.63–1.48) | 1.70 (1.34–2.14) |
| Multivariable HR (95% CI) | 1.00 | 0.64 (0.31–1.31) | 0.94 (0.61–1.44) | 1.60 (1.26–2.04) |
| PAF (95% CI) | … | … | 17.7 (8.2–26.2) | |
| Women, n | 8776 | 806 | 1643 | 882 |
| No. of patient‐y | 80 776 | 7867 | 15 784 | 7831 |
| No. of cases | 142 | 3 | 30 | 33 |
| Age‐ and area‐adjusted HR (95% CI) | 1.00 | 0.25 (0.08–0.77) | 0.96 (0.65–1.43) | 1.66 (1.13–2.46) |
| Multivariable HR (95% CI) | 1.00 | 0.25 (0.08–0.77) | 0.98 (0.66–1.46) | 1.71 (1.16–2.54) |
| PAF (95% CI) | – | – | 6.6 (0.8–12.1) | |
| Age, 65–74 y | ||||
| Men, n | 1521 | 95 | 1146 | |
| No. of patient‐y | 12 582 | 785 | 8534 | |
| No. of cases | 127 | 6 | 105 | |
| Age‐ and area‐adjusted HR (95% CI) | 1.00 | 0.75 (0.33–1.71) | 1.23 (0.95–1.60) | |
| Multivariable HR (95% CI) | 1.00 | 0.75 (0.33–1.71) | 1.23 (0.95–1.61) | |
| PAF (95% CI) | – | – | ||
| Women, n | 2523 | 115 | 1286 | |
| No. of patient‐y | 21 707 | 981 | 10 922 | |
| No. of cases | 148 | 3 | 99 | |
| Age‐ and area‐adjusted HR (95% CI) | 1.00 | 0.55 (0.17–1.72) | 1.31 (1.02–1.70) | |
| Multivariable HR (95% CI) | 1.00 | 0.55 (0.17–1.72) | 1.31 (1.01–1.69) | |
| PAF (95% CI) | … | 9.4 (0.3–18.1) | ||
BMI indicates body mass index; CVD, cardiovascular disease; ISI, intensive support intevention; ISO, information supply only; MSI, motivation‐support intervention; and PAF, population attributable fraction. Multivariable hazard ratio (HR): adjusted further for non–high‐density lipoprotein (HDL) cholesterol. For ages 65 to 74 years, the ISI was collapsed into MSI.