Figure 2. Associations of (A) dietary and (B) circulating alpha‐linolenic acid (ALA) with coronary heart disease mortality in 4067 patients with post‐myocardial infarction.

Solid lines are risk estimates evaluated by restricted cubic splines from Cox models showing the shape of the associations on a continuous scale with 5 knots located at 5th, 27.5th, 50th, 72.5th, and 95th percentiles. The y‐axis shows the multivariable‐adjusted hazard ratios for coronary heart disease mortality risk for any dietary or circulating ALA value, compared with the reference values set at fifth percentile of dietary (0.49 g/d) or circulating ALA (0.30% of total fatty acids). Gray areas indicated 95% CIs. One SD of circulating ALA was 0.14% of total fatty acids. Histograms depict the distributions of dietary or circulating ALA in the Alpha Omega Cohort. ALA indicates alpha‐linolenic acid; and FA, fatty acids.