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. 2021 Nov 30;10(23):e021995. doi: 10.1161/JAHA.121.021995

Figure 2. Lipoprotein subclass associations with incident coronary artery disease (CAD) (2073 incident events; red) and peripheral artery disease (PAD) (498 incident events; dark blue).

Figure 2

Hazard ratios (HRs) and 95% CIs are shown per 1‐SD higher biomarker concentration, with numerical results indicated on the right‐hand side. Models are adjusted for sex and age. Open circles denote P≥0.0005, and closed circles denote P<0.0005. Asterisks denote P<0.001 for heterogeneity between PAD and CAD associations. Average particle sizes of the 14 lipoprotein subclasses (from XXL VLDL to S HDL) are defined in Reference 18. HDL indicates high‐density lipoprotein; IDL, intermediate‐density lipoprotein; LDL, low‐density lipoprotein; P, particle concentration; P‐het, P value for heterogeneity; and VLDL, very‐low‐density lipoprotein.