Table 3.
The Adjusted Mean of Metabolic Risk Factors at Baseline Among Individuals Who Did and Did Not Develop Hypertension
| Men (n=2191) | Women (n=3183) | P for sex difference | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
Without hypertension (n=1700) |
With hypertension (n=491) |
P value* |
Without hypertension (n=2525) |
With hypertension (n=658) |
P value* | Without hypertension | With hypertension | P interaction † | P interaction ‡ | |
| BMI, kg/m2 | 24.8 (0.1) | 26.1 (0.2) | <0.001 | 25.7 (0.1) | 28.1 (0.1) | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| WC, cm | 85.6 (0.2) | 88.2 (0.4) | <0.001 | 82.2 (0.4) | 87.5 (0.4) | <0.001 | <0.001 | 0.273 | <0.001 | <0.001 |
| FPG, mmol/L | 5.03 (0.02) | 5.07 (0.04) | 0.359 | 4.89 (0.01) | 5.08 (0.03) | <0.001 | <0.001 | 0.894 | 0.023 | 0.025 |
| SBP, mm Hg | 110.1 (0.2) | 116.3 (0.4) | <0.001 | 106.5 (0.1) | 115.0 (0.3) | <0.001 | <0.001 | 0.020 | 0.001 | 0.001 |
| DBP, mm Hg | 72.2 (0.1) | 77.3 (0.3) | <0.001 | 71.5 (0.1) | 77.4 (0.3) | <0.001 | 0.002 | 0.677 | 0.067 | 0.056 |
| HDL‐C, mmol/L | 0.97 (0.01) | 0.96 (0.01) | 0.503 | 1.17 (0.01) | 1.12 (0.01) | <0.001 | <0.001 | <0.001 | 0.073 | 0.051 |
| Ln‐triglycerides, mmol/L | 0.46 (0.01) | 0.57 (0.02) | <0.001 | 0.21 (0.01) | 0.40 (0.02) | <0.001 | <0.001 | <0.001 | 0.032 | 0.069 |
| TC, mmol/L | 4.96 (0.02) | 5.17 (0.04) | <0.001 | 4.95 (0.02) | 5.10 (0.04) | 0.001 | 0.735 | 0.277 | 0.422 | 0.292 |
Values show the mean (SE) adjusted for baseline age in ANCOVA model. BMI indicates body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL‐C, high‐density lipoprotein cholesterol; Ln‐triglycerides, natural logarithm of triglyceride; SBP, systolic blood pressure; TC, total cholesterol; and WC, waist circumference.
P values were adjusted by Bonferroni method and show the statistical difference between those with and without hypertension.
P value shows the significance of interaction term of sex by hypertension status in ANCOVA model adjusted for baseline age.
P value shows the significance of interaction term of sex by hypertension status in ANCOVA model adjusted for baseline age, smoking status, physical activity level, and family history of cardiovascular disease.