Table 4.
Adjusted Mean of AUC of Metabolic Risk Factors Among Individuals Who Did and Did Not Develop Hypertension
| Men (n=2191) | Women (n=3183) | P for sex difference | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
Without hypertension (n=1700) |
With hypertension (n=491) |
P value* |
Without hypertension (n=2525) |
With hypertension (n=658) |
P value* |
Without hypertension |
With hypertension | P interaction † | P interaction ‡ | |
| AUC measures (ʃ) | ||||||||||
| BMI, kg/m2 | 26.3 (0.1) | 27.8 (0.2) | <0.001 | 27.8 (0.2) | 30.3 (0.1) | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| WC, cm | 92.5 (0.2) | 96.2 (0.4) | <0.001 | 90.2 (0.2) | 95.9 (0.3) | <0.001 | <0.001 | 0.578 | <0.001 | <0.001 |
| FPG, mmol/L | 5.6 (0.02) | 5.6 (0.04) | 0.074 | 5.3 (0.01) | 5.5 (0.03) | <0.001 | <0.001 | 0.087 | 0.007 | 0.009 |
| SBP, mm Hg | 113.6 (0.2) | 121.3 (0.3) | <0.001 | 109.2 (0.1) | 121.0 (0.3) | <0.001 | <0.001 | 0.525 | <0.001 | <0.001 |
| DBP, mm Hg | 74.9 (0.1) | 79.7 (0.2) | <0.001 | 72.2 (0.1) | 78.2 (0.1) | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| HDL‐C, mmol/L | 1.1 (0.01) | 1.1 (0.01) | 0.232 | 1.3 (0.01) | 1.2 (0.01) | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| Ln‐triglycerides, mmol/L | 0.4 (0.01) | 0.5 (0.01) | <0.001 | 0.2 (0.01) | 0.4 (0.01) | <0.001 | <0.001 | <0.001 | 0.003 | 0.006 |
| TC, mmol/L | 4.81 (0.01) | 4.89 (0.02) | 0.012 | 4.96 (0.01) | 5.04 (0.02) | 0.003 | <0.001 | <0.001 | 0.957 | 0.882 |
Values were adjusted for baseline age in ANCOVA model. BMI indicates body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL‐C, high‐density lipoprotein cholesterol; Ln‐triglycerides, natural logarithm of triglyceride; SBP, systolic blood pressure; TC, total cholesterol; and WC, waist circumference.
P values were adjusted by Bonferroni method and show the statistical difference between those with and without hypertension.
P value shows the significance of interaction term of sex by hypertension status in ANCOVA model adjusted for baseline age.
P value shows the significance of interaction term of sex by hypertension status in ANCOVA model adjusted for baseline age, smoking status, physical activity level and family history of CVD.