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. 2022 Mar 18;11(7):e023146. doi: 10.1161/JAHA.121.023146

Table 6.

Associations With Investigation or Intervention in Those With Unattributed Chest Pain and Cardiovascular Risk ≥10% at Baseline in Aurum

Investigation, OR (95% CI)

New lipid‐lowering prescription,*

OR (95% CI)

Age, y
18–44 0.96 (0.88–1.06) 0.80 (0.67–0.96)
45–54 1 1
55–64 0.98 (0.94–1.03) 1.16 (1.07–1.26)
65–74 0.94 (0.89–0.98) 1.27 (1.16–1.38)
75+ 0.81 (0.76–0.85) 0.89 (0.80–0.99)
Sex
Men 1 1
Women 0.90 (0.88–0.93) 0.99 (0.93–1.05)
Race
Other ethnic groups 1 1
White 1.19 (1.09–1.31) 1.06 (0.95–1.18)
Deprivation
Least 1 1
2nd 0.95 (0.90–1.00) 0.97 (0.90–1.05)
3rd 0.90 (0.85–0.95) 0.99 (0.91–1.08)
4th 0.84 (0.79–0.90) 1.05 (0.96–1.15)
Most 0.69 (0.63–0.75) 1.04 (0.95–1.13)
Diabetes, type 2 0.85 (0.81–0.89) 1.82 (1.66–2.00)
FH
Angina/heart attack age <60 y 1.45 (1.37–1.53) 1.74 (1.60–1.89)
Chronic kidney disease stage 3–5 0.98 (0.94–1.02) 0.85 (0.77–0.94)
Atrial fibrillation 1.51 (1.39–1.63) 1.13 (0.96–1.32)
Treated hypertension 0.92 (0.89–0.95) 1.05 (1.00–1.11)
Total/HDL ratio
≤4 1 1
4–6 1.04 (1.01–1.08) 1.52 (1.44–1.62)
>6 1.02 (0.96–1.08) 2.68 (2.45–2.95)
Not recorded 0.55 (0.52–0.59) 0.32 (0.29–0.36)
BMI
Normal 1 1
Underweight 0.79 (0.69–0.89) 0.72 (0.54–0.96)
Overweight 1.10 (1.07–1.14) 1.20 (1.13–1.29)
Obese 1.14 (1.10–1.19) 1.29 (1.19–1.39)

BMI indicates body mass index; FH, family history; HDL, high‐density lipoprotein; and OR, odds ratio.

*

In those with no lipid‐lowering prescription in 24 mo before index date, n=79 726.

Missing data means not recorded (not presented here).