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. 2022 Mar 18;11(7):e022694. doi: 10.1161/JAHA.121.022694

Figure 4. Graph displaying freedom from pulmonary valve replacement (PVR) procedures during follow‐up using Kaplan‐Meier curves (displayed with 95% CIs).

Figure 4

The study population was divided into different subgroups according to the peak right ventricular outflow tract (RVOT) gradient <15, 15 to 30, and >30 mm Hg and the severity of pulmonary regurgitation (PR; <25% and ≥25%). Statistical comparisons between the subgroups were made using the log‐rank (Mantel‐Cox) test (P values are displayed in Table S3). Note that in patients with PR ≥25% (top panel), no significant difference in the need for PVR surgery was observed between the subgroups, suggesting that mild residual RVOT stenosis seems not to protect from PVR. In patients with PR <25% (bottom panel), the subgroup with a peak RVOT gradient >30 mm Hg had a significant higher risk for PVR during follow‐up than those with a gradient <15 and 15 to 30 mm Hg (P<0.001, respectively). CMR indicates cardiovascular magnetic resonance.