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. 2022 Mar 18;11(7):e022694. doi: 10.1161/JAHA.121.022694

Table 3.

Cox Proportional Hazard Analysis Using a Bivariable Model of the Parameters That Reached a Significant Level on Univariable Testing to Identify Their Prognostic Relevance in Conjunction With the Peak RVOT Gradient

Parameter HR 95% CI P value
RVOT gradient, mm Hg 1.03 1.00–1.05 0.025*
Peak VO2 at VAT, mL/min per kg 0.93 0.88–0.98 0.01*
RVOT gradient, mm Hg 1.03 1.00–1.06 0.016*
LVEDVi, mL/m2 1.03 1.01–1.05 0.003*
RVOT gradient, mm Hg 1.04 1.00–1.06 0.007*
LVESVi, mL/m2 1.03 1.02–1.05 <0.001*
RVOT gradient, mm Hg 1.03 1.00–1.06 0.05
RV‐LS, % 1.17 1.02–1.35 0.023*
RVOT gradient, mm Hg 1.03 1.00–1.06 0.045*
LV‐CS (%) 1.14 1.04–1.24 0.006*

CS indicates circumferential strain; HR, hazard ratio; LS, longitudinal strain; LV, left ventricular; LVEDVi, left ventricular end‐diastolic volume; LVESVi, left ventricular end‐systolic volume; RV, right ventricular; RVOT, RV outflow tract; VAT, ventilator anaerobic threshold; and VO2, oxygen uptake.

*

indicates statistical significance (P<0.05).