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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Circ Res. 2022 Feb 25;130(7):981–993. doi: 10.1161/CIRCRESAHA.121.320436

Figure 6: Human B1 cells from subjects with an ID3 SNP at rs11574, known to attenuate Id3 function, have increased P62 expression; a finding associated with B1 frequency and plasma IgM to MDA-LDL levels.

Figure 6:

(A) MFI of P62 within P62+ population in human total B and human B1 (CD27+CD43+) cells across major (n = 36), heterozygous (n = 17), and minor allele (n = 5) ID3 rs11574 SNP otherwise age and sex matched. (B-C) correlations between IgM specific to MDL mimotope (B) with P62 expression (n = 58), and IgG specific to MDL mimotope with P62 expression (n = 58) (C). Results were represented with Mean ± SD. Statistical analyses were performed using Kruskal-Wallis test with Dunn’s correction for multiple comparison and correlation analysis was performed by using Spearman correlation.