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. 2019 Nov 13;9(64):37127–37135. doi: 10.1039/c9ra08245j

Fig. 6. PGM aggrandized glial cell activation in the hippocampal regions of APP/PS1 mice. (A) Fluorescent GFAP (red)/DAPI (blue) colocalization in the DG regions of the hippocampus in APP/PS1 mice. Scale bar = 100 μm. (B) Fluorescent GFAP (red)/DAPI (blue) colocalization in the DG regions of the hippocampus in WT mice. Scale bar = 100 μm. (C) Fluorescent Iba1 (red)/DAPI (blue) colocalization in the DG regions of the hippocampus in APP/PS1 mice. Scale bar = 100 μm. (D) Fluorescent Iba1 (red)/DAPI (blue) colocalization in the DG regions of the hippocampus in WT mice. Scale bar = 100 μm. (E) Quantification of GFAP-positive cells in each APP/PS1 mice group. n = 5–8 per group, three sections per animal. (F) Quantification of GFAP-positive cells in each WT mice group. n = 5–8 per group, three sections per animal. (G) Quantification of Iba1-positive cells in each APP/PS1 mice group. n = 5–8 per group, three sections per animal. (H) Quantification of Iba1-positive cells in each WT mice group, n = 5–8 per group, three sections per animal. *P < 0.05 vs. APP/PS1-saline, **P < 0.01 vs. APP/PS1-saline.

Fig. 6