Weight changes in each group of mice during the period of PGM treatment. Data are expressed as mean ± SD (n = 12 per group).
6th month | 6th month + 2nd week | 7th month | 7th month + 2nd week | 8th month | 8th month + 2nd week | 9th month | 9th month + 1st week | |
---|---|---|---|---|---|---|---|---|
APP/PS1-saline | 26.57 ± 1.96 | 26.73 ± 2.59 | 26.53 ± 2.57 | 25.6 ± 2.09 | 25.23 ± 1.95 | 25.25 ± 2.93 | 25.56 ± 1.85 | 25.85 ± 2.01 |
APP/PS1-PGM 5 | 29.06 ± 3.14 | 28.68 ± 3.28 | 28.72 ± 3.27 | 28.72 ± 3.10 | 28.86 ± 3.00 | 29.82 ± 3.14 | 30.94 ± 3.68 | 31.44 ± 3.46 |
APP/PS1-PGM 10 | 28.97 ± 3.87 | 28.49 ± 3.83 | 29.18 ± 3.78 | 27.83 ± 3.39 | 28.31 ± 4.29 | 27.84 ± 3.38 | 30.46 ± 3.58 | 31.33 ± 4.09 |
APP/PS1-PGM 20 | 28.03 ± 4.30 | 27.25 ± 3.92 | 27.14 ± 4.03 | 27.87 ± 3.89 | 28.02 ± 3.87 | 27.89 ± 3.75 | 28.96 ± 4.17 | 29.16 ± 4.16 |
WT-saline | 27.34 ± 3.71 | 26.81 ± 3.18 | 26.00 ± 3.14 | 26.37 ± 2.99 | 26.05 ± 3.19 | 26.09 ± 3.50 | 26.15 ± 2.16 | 26.02 ± 1.95 |
WT-PGM 5 | 29.11 ± 3.22 | 28.35 ± 3.45 | 28.43 ± 3.07 | 28.55 ± 2.96 | 27.86 ± 2.86 | 28.04 ± 2.40 | 28.6 ± 2.48 | 28.57 ± 2.40 |
WT-PGM 10 | 29.00 ± 2.27 | 28.62 ± 2.27 | 28.05 ± 1.93 | 27.99 ± 1.99 | 27.36 ± 2.26 | 28.06 ± 2.08 | 29.06 ± 2.05 | 29.21 ± 2.08 |
WT-PGM 20 | 28.91 ± 1.78 | 27.52 ± 2.10 | 27.64 ± 2.43 | 28.09 ± 1.92 | 27.97 ± 1.90 | 28.39 ± 1.96 | 29.07 ± 1.97 | 29.43 ± 1.55 |