Fig. 5. CytoZ11 attenuated NFATc1 activation, c-Fos signaling. (A) Typical images of the western blot demonstrating the effects of CytoZ11 on the protein expression of NFATc1, c-Fos, Ctsk, integrin αV during RANKL-induced osteoclastogenesis. Quantification of ratios of band intensity of (B) c-Fos, (C) NFATc1, (D) CTSK, and (E) integrin αV relative to β-actin. *p < 0.05, **p < 0.01 relative to RANKL-induced control group. CytoZ11: cytochalasin Z11; RANKL: receptor activator of nuclear factor-κB ligand; NFATc1: nuclear factor of activated T cells 1.
