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. 2019 Nov 27;9(67):38912–38927. doi: 10.1039/c9ra05608d

Fig. 8. Effects of different concentrations of silibinin, CGONP-S, CGONP-E, and extract (E) on cell viability in normal and high-glucose conditions. Cells were treated with silibinin, extract, CGONP-S, and CGONP-E at various concentrations for 48 h. CGONP-S, silibinin (S), CGONP, *P < 0.05 vs. control, **P < 0.001 vs. control. ##P < 0.001 vs. control HG. Normal glucose (NG), high glucose (HG), high mannitol (HM), NG plus Silibinin (S-NG), HG plus Silibinin (S-HG), NG plus Extract (E-NG), HG plus Extract (E-HG), NG plus Citric acid–Glycerol–Oleic acid Nanopolymer Silibinin (NG-CGONP-S), HG plus Citric acid–Glycerol–Oleic acid Nanopolymer Silibinin (HG-CGONP-S), NG plus extract Citric acid–Glycerol–Oleic acid Nanopolymer (E-CGONP-NG), HG plus extract Citric acid–Glycerol–Oleic acid Nanopolymer (E-CGONP-HG).

Fig. 8