Table 2.
Recognition of antigens from SARS-CoV-2 variants by ovine antibody preparations.
| Ovine antibody preparation |
|||
|---|---|---|---|
| Full-length | S1 subunit | S2 subunit | |
| SARS-CoV-2 RBD (B.1.1.7) | 99.197 | 78.347 | 2.180 |
| SARS-CoV-2 RBD (P.1) | 97.214 | 75.465 | 14.960 |
| SARS-CoV-2 S1 RBD | 99.757 | 84.056 | 13.977 |
| SARS-CoV-2 S1 RBD (B.1.351) | 98.309 | 87.894 | 50.711 |
| SARS-CoV-2 Spike | 99.795 | 58.721 | 49.074 |
| SARS-CoV-2 Spike (B.1.1.7) | 98.831 | 26.369 | 22.948 |
| SARS-CoV-2 Spike (B.1.351) | 95.801 | 18.956 | 30.435 |
| SARS-CoV-2 Spike (P.1) | 96.395 | 20.529 | 35.644 |
Data show percentage inhibition of ACE2 binding using a MesoScale Discovery assay with each antibody preparation being standardised to a concentration of 1 mg/ml.