Fig. 4. Comparison of the interaction of paliperidone–MALT1 complex and MLT-747–MALT1 complex. Chemical structures of MLT-747 (A) and paliperidone (B). The structure superposition between MLT-747 and paliperidone docked into the allosteric site of MALT1, the protein was shown by vacuum electrostatics potential (C), and cartoon (D). The inhibitors were shown in stick model representation with different colors of carbon skeleton: MLT-747 was shown in magenta and paliperidone was shown in yellow. Compared 2D interaction of MALT1 with MLT-747 (E) or paliperidone (F). Green dotted lines represented the hydrogen bonding.