Comparison of the selected distances in MALT1 catalytically active sites at the active/inactive conformational state.

Protein state	PDB ID	Inhibitor properties	Inhibitor	C464:SG–Q494:Oa	R465:NH2–Q494:OE1a	L446:CD2–L480:CD1a
Active	3V4O	Active inhibitor	Oligopeptide	10.54	5.40	3.38
Active	4I1P	Active inhibitor	Oligopeptide	10.77	5.91	3.47
Inactive	6F7I	Allosteric inhibitor	MLT-747	4.13	14.69	14.24
Inactive	6H4A	Allosteric inhibitor	MLT-748	3.51	15.19	15.73
Inactive	3V55	—	—	5.01	13.41	15.75

^aThe length between two atoms (Å).