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. 2019 Nov 29;9(67):39410–39421. doi: 10.1039/c9ra06571g

In vitro inhibitory effect of quinoline-triazole based target compounds against recombinant FP2 and P. falciparum 3D7 (EC50) growth in vitro.

S. no. Compound Inhibition of FP2 IC50 (μM) Std. error Inhibition of P. falciparum EC50 (μM) Std. error
1 T1 26.59 5.45 49.50 10.54
2 T2 45.08 9.46 405.64 398.80
3 T3 25.38 3.18 159.22 150.16
4 T4 25.64 4.13 21.89 4.51
5 T5 107.32 135.24 66.57 45.08
6 T6 45.78 18.98 57.86 183.93
7 T7 16.16 3.03 49.88 7.41
8 T8 25.37 1.94 51.71 8.57
9 T9 20.9 4.15 146.98 345.29
10 T10 58.46 19.07 57.63 14.02