Table 2. Features and Severity of Gastrointestinal Toxicity Subtypes.

Characteristics	All GI adverse events, n (%)	Colitis, n (%)	Hepatitis, n (%)	Gastritis, n (%)	Pancreatitis, n (%)
Number of patients	41 (100)	17 (100)	23 (100)	2 (100)	4 (100)
Severity grade
1 or 2	23 (56.1)	7 (41.2)	16 (72.7)	2 (100)	2 (50.0)
3 or more	18 (43.9)	10 (58.8)	6 (27.3)	0 (0)	2 (50.0)
1	9 (22.0)	2 (11.8)	8 (34.8)	1 (50.0)	0 (0)
2	14 (34.1)	5 (29.4)	9 (39.1)	1 (50.0)	2 (50.0)
3	14 (34.1)	8 (47.0)	4 (17.4)	0 (0)	2 (50.0)
4	3 (7.3)	2 (11.8)	1 (4.3)	0 (0)	0 (0)
5	1 (2.4)	0 (0)	1 (4.3)	0 (0)	0 (0)
Dominant symptoms
Laboratory abnormalities only	16 (39.0)	0 (0)	15 (65.2)	0 (0)	1 (25.0)
Diarrhea	13 (31.7)	12 (70.6)	2 (8.7)	1 (50.0)	2 (50.0)
Abdominal pain	7 (17.1)	2 (11.8)	4 (17.4)	0 (0)	1 (25.0)
Abdominal pain and diarrhea	2 (4.9)	2 (11.8)	1 (4.3)	0 (0)	0 (0)
Severe fatigue	2 (4.9)	1 (5.9)	1 (4.3)	0 (0)	0 (0)
Dyspepsia	1 (2.4)	0 (0)	0 (0)	1 (50.0)	0 (0)
Treated with steroid
Yes (> 4 weeks)	27 (65.9)	10 (58.8)	18 (78.3)	1 (50.0)	1 (25.0)
Yes (< 4 weeks)	8 (19.5)	5 (29.4)	2 (8.7)	1 (50.0)	1 (25.0)
No	3 (7.3)	0 (0)	2 (8.7)	0 (0.0)	1 (25.0)
Unknown	3 (7.3)	2 (11.8)	1 (4.3)	0 (0.0)	1 (25.0)

GI: gastrointestinal.